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1859
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1859
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1869
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produced 1859 1860 1866 1869 1872
experimented on have been produced 1861

(I do not mean mere confinement) apparently 1860 1861
apparently 1859
(I do not mean mere confinement) almost certainly 1866 1869 1872

sterility, 1859 1860 1861 1866 1869
that sterility which, judging from analogy, would have affected the parent-species if intercrossed, 1872

it also to produce sterility. 1859 1860 1861 1866 1869
that domestication would likewise induce sterility in their modified descendants when crossed. 1872

10 blocks not present in 1859 1860 1861 1866 1869; present in 1872
This elimination of sterility apparently follows from the same cause which allows our domestic animals to breed freely under diversified circumstances; and this again apparently follows from their having been gradually accustomed to frequent changes in their conditions of life. A double and parallel series of facts seems to throw much light on the sterility of species, when first crossed, and of their hybrid offspring. On the one side, there is good reason to believe that slight changes in the conditions of life give vigour and fertility to all organic beings. We know also that a cross between the distinct individuals of the same variety, and between distinct varieties, increases the number of their offspring, and certainly gives to them increased size and vigour. This is chiefly owing to the forms which are crossed having been exposed to somewhat different conditions of life; for I have ascertained by a laborious series of experiments that if all the individuals of the same variety be subjected during several generations to the same conditions, the good derived from crossing is often much diminished or wholly disappears. This is one side of the case. On the other side, we know that species which have long been exposed to nearly uniform conditions, when they are subjected under confinement to new and greatly changed conditions, either perish, or if they survive, are rendered sterile, though retaining perfect health. This does not occur, or only in a very slight degree, with our domesticated productions, which have long been exposed to fluctuating conditions. Hence, when we find that hybrids produced by a cross between two distinct species are few in number, owing to their perishing soon after conception or at a very early age, or if surviving that they are rendered more or less sterile, it seems highly probable that this result is due to their having been in fact subjected to a great change in their conditions of life, from being compounded of two distinct organisations. He who will explain in a definite manner why, for instance, an elephant or a fox will not breed under confinement in its native country, whilst the domestic pig or dog will breed freely under the most diversified conditions, will at the same time be able to give a definite answer to the question why two distinct species, when crossed, as well as their hybrid offspring, are generally rendered more or less sterile, whilst two domesticated varieties when crossed and their mongrel offspring are perfectly fertile.

are 1859 1860 1861
of hybrids are 1866 1869

in 1859 1860 1861
of course in 1866 1869

their constitutions having been disturbed by slightly different and new conditions of life, 1859 1860 1861 1866
being exposed to slightly changed conditions, 1869

organisations. 1859 1860 1861 1866
organisations; but whether this is the true cause of their sterility I will not pretend to decide. 1869

acquire from being crossed 1859 1860 1861
when crossed acquire 1866 1869

produced under domestication; and as domestication (I do not mean mere confinement) apparently tends to eliminate sterility, we ought not to expect it also to produce sterility.
The sterility of hybrids is a
very
very
different case from that of
a first
first
cross,
crosses,
for
the
their
reproductive organs are more or less functionally impotent; whereas in first
crosses,
crosses
the organs
of
on
both
species
sides
are in a perfect condition. As we continually see that organisms of all kinds are rendered in some degree sterile from their constitutions having been disturbed by slightly different and new conditions of life, we need not feel surprise at hybrids being in some degree sterile, for their constitutions can hardly fail to
be
have been
disturbed from being compounded of two distinct organisations.
The above
This
parallelism is supported by another parallel, but directly opposite, class of
facts,
facts;
namely, that the vigour and fertility of all organic beings are increased by slight changes in their conditions of life, and that the offspring of slightly modified forms or varieties acquire from being crossed increased vigour and fertility. So that, on the one hand,
a considerable
considerable
change
changes
in the conditions of life and crosses between greatly modified forms, lessen fertility; and on the other hand, lesser changes in the conditions of life and crosses between less modified forms, increase fertility.
Turning to geographical distribution, the difficulties encountered on the theory of descent with modification are
serious
grave
enough. All the individuals of the same species, and all the species of the same genus, or even higher group,
are
must have
descended from common parents; and therefore, in however distant and isolated parts of the world they
may
are
now
be found,
found,
they must in the course of successive generations have
travelled
passed
from some one
point
part
to
all the
the
others. We are often wholly unable