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to the co-existence of man and the ornithorhynchus amongst mammalia— or of the shark and amphioxus, which latter fish in the extreme simplicity of its structure closely approaches the invertebrate classes. But mammals and fish hardly come into competition with each other; the advancement of certain mammals or of the whole class to the highest grade of organisation would not lead to their taking the place of, and thus exterminating, fishes. Physiologists believe that the brain must be bathed by warm blood to be highly active, and this requires aërial respiration; so that warm-blooded mammals when inhabiting the water live under some disadvantages compared with fishes. In this latter class, members of the shark family would not, it is probable, tend to supplant the amphioxus; the struggle for existence in the case of the amphioxus apparently will lie with members of the invertebrate classes. The three lowest orders of mammals, namely, marsupials, edentata, and rodents, co-exist in South America in the same region with numerous monkeys, and probably interfere little with each other. Although organisation, on the whole, may have advanced and be advancing throughout the world, yet the scale will still present all degrees of perfection; for the high advancement of certain whole classes, or of certain members of each class, does not at all necessarily lead to the extinction of those groups with which they do not enter into close competition. In some cases, as we shall hereafter see, lowly organised forms seem to have been preserved to the present day from inhabiting peculiar or isolated stations, where they have been subjected to less severe competition, and where they have existed in scanty numbers, which, as already explained, retards the chance of favourable variations arising.
Finally, I believe that lowly organised forms now